Health officials have raised alarms over declining diphtheria booster rates among older children in the Western Cape, warning that the region now accounts for the majority of toxigenic respiratory diphtheria cases in South Africa.
91 confirmed cases of toxigenic respiratory diphtheria nationwide (Jan 2024–Jan 2026).
67 cases reported in the Western Cape alone.
23% of cases occurred in children aged 12 and under.
Many affected children had no booster doses despite receiving infant vaccinations.
The Tdap booster (tetanus, diphtheria, pertussis) is critical at 6 and 12 years to maintain immunity.
Officials cite low uptake among older children, increasing vulnerability.
Free booster shots are available at public clinics and through school outreach programmes (with parental consent).
Shimoney Regter, Western Cape Health spokesperson:
“Lower uptake of booster doses reduces protection over time and increases risk of diphtheria.”
Foster Mohale, National Health spokesperson:
“Vaccine hesitancy and misinformation are fueling outbreaks of preventable diseases.”
The Big Catch-Up Campaign launched in November 2025, targeting districts hit by diphtheria, measles, and rubella.
Weekly virtual meetings between national and provincial health departments track progress.
Efforts include door-to-door awareness, social media campaigns, and school-based mobilization.
The Western Cape faces a preventable public health crisis, with officials urging parents to check vaccination records, return school consent forms, and visit clinics for missed booster doses.



